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                    [Title] => Chronic PPI use, hip fracture link confirmed
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Regular use of proton pump inhibitors is associated with an elevated risk of hip fractures, even after adjusting for important lifestyle risk factors, according to the findings of a prospective evaluation from the Nurses’ Health Study.

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                    [AuthorName] => Charles C. Chante MD
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                    [Title] => Progress on treating upper GI disorders
                    [Summary] => 
Barrett’s esophagus with dysplasia has traditionally been managed surgically and esophagectomy performed in centers of excellence may not be high-risk as previously thought, especially in otherwise fit individuals.
                    [DatePublished] => 2012-10-14 00:00:00
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                    [Title] => PPI adverse effects probably overstated, experts say
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‘There are interesting epidemiologic associations, but the magnitude is weak and findings are inconsistent.’
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                    [Title] => How to handle a heartburn
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The meal tastes great … until you lie down and your chest starts burning.
                    [DatePublished] => 2012-01-31 00:00:00
                    [ColumnID] => 133436
                    [Focus] => 0
                    [AuthorID] => 1778504
                    [AuthorName] => Tyrone M. Reyes M.D.
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                    [Title] => Link between PPI use and C. difficile strengthened
                    [Summary] => 
Use of proton pump inhibitors appears to increase the risk of recurrent clostridium difficile infection and may even have a causal effect, according to two cohort studies reported in the Archives of Internal Medicine.
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                    [Title] => For upper GI bleeds physicians still reach for the endoscope
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                    [DatePublished] => 2004-04-25 00:00:00
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                    [Title] => Once-daily PPI benefits many GERD patients
                    [Summary] => Positive results were achieved in terms of reducing healthcare costs and keeping patients asymptomatic in a recent testing of treatment guidelines for gastro-esophageal reflux disease. By following the guidelines which stipulate switching of gastroesophageal reflux disease (GERD) patients to single-dose proton pump inhibitors (PPIs) such as lansoprazole and omeprazole, researchers from the Department of Veterans Affairs Ann Arbor Healthcare System (VAAAHS), Michigan, found that medication costs dropped 53 percent, while 79.5 percent  of patients remained asymptomatic.
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PPIS

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                    [Title] => Chronic PPI use, hip fracture link confirmed
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Regular use of proton pump inhibitors is associated with an elevated risk of hip fractures, even after adjusting for important lifestyle risk factors, according to the findings of a prospective evaluation from the Nurses’ Health Study.

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                    [Title] => Progress on treating upper GI disorders
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Barrett’s esophagus with dysplasia has traditionally been managed surgically and esophagectomy performed in centers of excellence may not be high-risk as previously thought, especially in otherwise fit individuals.
                    [DatePublished] => 2012-10-14 00:00:00
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                    [Title] => PPI adverse effects probably overstated, experts say
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‘There are interesting epidemiologic associations, but the magnitude is weak and findings are inconsistent.’
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                    [Title] => How to handle a heartburn
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The meal tastes great … until you lie down and your chest starts burning.
                    [DatePublished] => 2012-01-31 00:00:00
                    [ColumnID] => 133436
                    [Focus] => 0
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                    [AuthorName] => Tyrone M. Reyes M.D.
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                    [Title] => Link between PPI use and C. difficile strengthened
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Use of proton pump inhibitors appears to increase the risk of recurrent clostridium difficile infection and may even have a causal effect, according to two cohort studies reported in the Archives of Internal Medicine.
                    [DatePublished] => 2012-01-15 00:00:00
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                    [Title] => For upper GI bleeds physicians still reach for the endoscope
                    [Summary] => Is endoscopic hemostasis obselete in the era of high-dose proton-pump inhibitors (PPIs)? Without a doubt, no – and yes. The role of endoscopic hemostasis for high-risk upper gastrointestinal (UGI) bleeding is assured, according to experts, while the success of PPIs provides a dependable adjunct for lowering the risk of rebleeding and for treating low-risk lesions. There is still absolutely a need for endoscopic hemostasis for many patients with upper gastrointestinal bleeding.
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                    [Title] => Once-daily PPI benefits many GERD patients
                    [Summary] => Positive results were achieved in terms of reducing healthcare costs and keeping patients asymptomatic in a recent testing of treatment guidelines for gastro-esophageal reflux disease. By following the guidelines which stipulate switching of gastroesophageal reflux disease (GERD) patients to single-dose proton pump inhibitors (PPIs) such as lansoprazole and omeprazole, researchers from the Department of Veterans Affairs Ann Arbor Healthcare System (VAAAHS), Michigan, found that medication costs dropped 53 percent, while 79.5 percent  of patients remained asymptomatic.
                    [DatePublished] => 2003-11-16 00:00:00
                    [ColumnID] => 136231
                    [Focus] => 0
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                    [AuthorName] => Charles C. Chante MD
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abtest

Chronic PPI use, hip fracture link confirmed

By YOUR DOSE OF MEDICINE | By Charles C. Chante MD | February 16, 2014 - 12:00am

Regular use of proton pump inhibitors is associated with an elevated risk of hip fractures, even after adjusting for important lifestyle risk factors, according to the findings of a prospective evaluation from the...

Opinion

Progress on treating upper GI disorders

By YOUR DOSE OF MEDICINE | By Charles C. Chante MD | October 14, 2012 - 12:00am

Barrett’s esophagus with dysplasia has traditionally been managed surgically and esophagectomy performed in centers of excellence may not be high-risk as previously thought, especially in otherwise fit in...

Opinion

PPI adverse effects probably overstated, experts say

By YOUR DOSE OF MEDICINE | By Charles C. Chante MD | February 26, 2012 - 12:00am

‘There are interesting epidemiologic associations, but the magnitude is weak and findings are inconsistent.’

Opinion

How to handle a heartburn

By Tyrone M. Reyes M.D. | January 31, 2012 - 12:00am

The meal tastes great … until you lie down and your chest starts burning.

Health And Family

Link between PPI use and C. difficile strengthened

By YOUR DOSE OF MEDICINE | By Charles C. Chante MD | January 15, 2012 - 12:00am

Use of proton pump inhibitors appears to increase the risk of recurrent clostridium difficile infection and may even have a causal effect, according to two cohort studies reported in the Archives of Internal Me...

Opinion

For upper GI bleeds physicians still reach for the endoscope

By YOUR DOSE OF MEDICINE | By Charles C. Chante MD | April 25, 2004 - 12:00am

Is endoscopic hemostasis obselete in the era of high-dose proton-pump inhibitors (PPIs)? Without a doubt, no – and yes. The role of endoscopic hemostasis for high-risk upper gastrointestinal (UGI) bleeding is...

Opinion

Once-daily PPI benefits many GERD patients

By YOUR DOSE OF MEDICINE | By Charles C. Chante MD | November 16, 2003 - 12:00am

Positive results were achieved in terms of reducing healthcare costs and keeping patients asymptomatic in a recent testing of treatment guidelines for gastro-esophageal reflux disease. By following the guidelines...

Opinion