Guba, a former junior standout from Bacolod City, survived Jeremiah Sison, 6-1, 6-7, 6-2, in the second singles match.
Joseph Nicholas Faller scored La Salles first point with a hard-earned 6-4, 4-6, 6-4 victory over Junji Guadayo in the first singles match.
The Fighting Maroons fought back and won the doubles behind Jericho Sison and Alexander Borela Jr., who scored a 6-3, 6-4, win over Andre Cruz and Gino Almario.
Ateneo de Manila, runnerup to champion University of Santo Tomas last year, conquered University of the East, 2-1, in the other game.
Neil Co defeated Jerry Bernabe, 6-1, 6-2, and Inigo Bautista and Francisco Gerard Abacan demolished Christian Banato and Jhune Llira, 6-1, 6-0.
The Red Warriors averted a rout when Peter Perpetua downed Mark Timbleque, 6-2, 6-2, in the second singles.
Winners in the womens division were defending champion UST over Ateneo, 3-0, and De La Salle over University of the Philippines, 2-1.