LIST: Pedro Almodovar's end-of-life film, other winners of the 81st Venice Film Festival

VENICE, Italy — Spain's Pedro Almodovar won Venice's Golden Lion award Saturday for his pro-euthanasia film "The Room Next Door," with the acting prizes going to Nicole Kidman and Frenchman Vincent Lindon.

The female friendship end-of-life film starring Tilda Swinton and Julianne Moore was Almodovar's first English-language feature-length film.

In the film — which like many of Almodovar's hinges on strong female characters — Swinton plays a war correspondent suffering from terminal cancer. She asks her friend, played by Moore, to be at her side when she takes her own life.

"I believe saying goodbye to this world cleanly and with dignity is a fundamental right of every human being," Almodovar told the audience after accepting his award. "It is not a political issue, but a human one."

He acknowledged that "this right goes against any religion or creed that has God as the only source of life."

"I would ask practitioners of any creed to respect and not intervene in individual decisions in this regard," said the prolific director, whose films in recent years have considered themes of death or physical decline.

President of the jury, French actor Isabelle Huppert, said the film tackled important issues thoughtfully and without melodrama. She paid tribute, too, to the performances of the two lead actors.

The 81st edition of the Venice Film Festival concluded on Saturday with the award ceremony.

Here are the main winners from among 21 films in competition, as decided by a jury chaired by French actor Isabelle Huppert:

Golden Lion for Best Film - "The Room Next Door" by Pedro Almodovar (Spain)
Silver Lion Grand Jury Prize - "Vermiglio" by Maura Delpero (Italy, France, Belgium)
Silver Lion Award for Best Director - Brady Corbet for "The Brutalist" (UK)
Volpi Cup Aaward for Best Actress - Nicole Kidman for "Babygirl" by Halina Reijn (US)
Volpi Cup Award for Best Actor - Vincent Lindon in "Jouer Avec Le Feu" by Delphine Coulin and Muriel Coulin (France)
Award for Best Screenplay - Murilo Hauser and Heitor Lorega for "I'm Still Here" by Walter Salles (Brazil, France)
Special Jury Prize - "April" by Dea Kulumbegashvili (France, Italy, Georgia)
Marcello Mastroianni Award for Best Young Actor or Actress - Paul Kircher for "Leurs Enfants Apres Eux" by Ludovic Boukherma and Zoran Boukherma (France)